A Russian drone slammed into a home in Ukraine’s northeastern Kharkiv region overnight, killing a father and his three small children and wounding their pregnant mother, Ukrainian officials said Wednesday, in one of the deadliest single-family attacks in recent months.

Tropical Cyclone Gezani collapsed houses in Madagascar’s main port city of Toamasina and left at least 31 people dead as it tore across the Indian Ocean island with powerful winds and heavy rain, authorities said Wednesday.

Iran warned Wednesday that its missile capabilities are “non-negotiable” as tensions increased with the United States, which appears to be preparing military options, even as the Islamic Republic faces unrest at home following a deadly nationwide protest crackdown.

Authorities in the United States intensified efforts Wednesday to find Nancy Guthrie, the 84-year-old mother of NBC’s “Today” show co-host Savannah Guthrie, after law enforcement briefly detained and then released an initial suspect.

Israeli President Isaac Herzog has met victims’ families and survivors of Australia’s worst-ever terrorist and antisemitic attack that killed more than a dozen people, amid mounting tensions between the two nations.

Efforts to dismantle Hamas’ military infrastructure in Gaza are moving forward according to plan, despite tensions surrounding the ceasefire, a senior official involved in U.S. President Donald Trump’s Board of Peace initiative told Ynet in an exclusive report Wednesday.

As diplomatic talks continue between Washington and Tehran, new reports from inside Iran describe intensifying repression and widespread fear among ordinary citizens.

U.S. President Donald Trump met privately with Israeli Prime Minister Benjamin Netanyahu at the White House for nearly three hours Wednesday, with both leaders confirming that negotiations with Iran remain ongoing but no final agreement has been reached.

The Pentagon has instructed a second aircraft carrier strike group to prepare for potential deployment to the Middle East as the United States increases military readiness in response to rising tensions with Iran, according to The Wall Street Journal.

Authorities in the U.S. state of Arizona detained a suspect Tuesday in connection with the reported abduction of Nancy Guthrie, the 84-year-old mother of American television host Savannah Guthrie, as the high-profile investigation entered its ninth day.