Israel’s Defense Minister, Israel Katz, has threatened to assassinate Iranian Ayatollah Ali Khamenei after one or more Iranian ballistic missiles struck the hospital in Beersheba, the main city in Israel’s Negev desert.

Iran launched about 20 powerful ballistic missiles toward Israel, and at least one of them struck Soroka Hospital in Beersheba, the largest city in the Negev desert of southern Israel, officials and witnesses said.

Israel is facing a critical shortage of its Arrow missile interceptors, raising alarm over its ability to defend against long-range ballistic missiles from Iran as the conflict continues without resolution, The Wall Street Journal reported Wednesday, citing a U.S. official.

Iranian Supreme Leader Ayatollah Ali Khamenei on Wednesday vowed that his nation “will never surrender,” defiantly rejecting President Donald Trump’s call for Iran’s “unconditional surrender” as Israeli airstrikes pummeled targets across Iran for a sixth consecutive day.

The Israel Defense Forces (IDF) announced Tuesday that its campaign against Iran’s nuclear program and ballistic missile capabilities is on track to achieve its objectives within a week or two. The military’s estimate came as Israeli fighter jets and drones carried out a fresh wave of airstrikes, targeting Iranian ballistic missile launchers, air defense systems, and radar sites across western and central Iran.

Iranian Supreme Leader Ayatollah Ali Khamenei issued chilling threats Tuesday night, declaring “the battle begins” and vowing no mercy for Israel, as U.S. President Donald Trump considered launching American strikes on Iranian targets.

President Donald Trump on Tuesday shared a powerful message from U.S. Ambassador to Israel Mike Huckabee, underscoring the belief that God’s hand is guiding America’s leadership during this critical moment in the Middle East.

In the midst of ongoing military operations across Iran, an Israeli official has confirmed that the country is actively preparing to mitigate potential contamination resulting from strikes on Iranian nuclear facilities, including the heavily fortified Fordow Fuel Enrichment Plant.

The head of the International Atomic Energy Agency (IAEA), Rafael Grossi, confirmed on Monday that Israel’s recent airstrikes on Iran have likely inflicted catastrophic damage on the country’s uranium enrichment capabilities, delivering a major setback to Tehran’s nuclear program.

Massive explosions were seen across Tehran after U.S. President Donald J. Trump urged citizens to evacuate the Iranian capital, while Israel suffered deadly Iranian strikes, including on its northern city of Haifa and oil refinery facilities in the area.

Israeli Prime Minister Benjamin Netanyahu told ABC News that assassinating Iran’s Supreme Leader Ali Khamenei would not intensify the conflict between Israel and Iran, but would instead bring it to an end.

Iranian missiles triggered sirens across northern Israel on Monday after the death toll of previous strikes launched by Tehran and its Houthi allies in Yemen rose to at least 25, with hundreds injured, officials said.

The Israeli Air Force (IAF) struck the headquarters of Iran’s state-affiliated broadcaster, Islamic Republic of Iran Broadcasting (IRIB), during a live transmission Monday afternoon, following an unprecedented evacuation warning issued to residents of northern Tehran. The attack marked a dramatic escalation in the ongoing conflict between Israel and Iran.

The Israeli military announced Monday that it has achieved air superiority over Tehran, following a series of precision airstrikes that killed four of Iran’s top intelligence officials and crippled much of the regime’s missile-launching capability. The strikes are part of Operation Rising Lion, Israel’s large-scale campaign launched last Thursday in response to Iran’s escalating aggression

Israeli Prime Minister Benjamin Netanyahu on Friday announced that Israel’s military offensive in Iran is designed not only to dismantle the Islamic Republic’s nuclear and missile threats, but also to open the door for the Iranian people to claim their freedom from what he called an “evil and oppressive regime.”